Eptifibatide maka ọgwụgwọ nke nnukwu ọrịa coronary 188627-80-7
Nkọwa ngwaahịa
| Aha | Eptifibatide |
| Nọmba CAS | 188627-80-7 |
| Usoro ihe omimi | C35H49N11O9S2 |
| Ibu arọ molekụla | 831.96 |
| Nọmba EINECS | 641-366-7 |
| Njupụta | 1.60±0.1 g/cm3 (buru amụma) |
| Ọnọdụ nchekwa | E mechiri ya na nkụ, chekwaa ya na friza, n'okpuru -15 Celsius |
Ụdị okwu
Eptifibatideacetatesalt;Eptifibatide,MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2,MPAHARGDWPC-NH2,>99%;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide(Amin); nomethyl) -N2- (3-mercapto-1-oxopropyl-L-lysylglycyl-La-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDEBRIDGE,MPA1-CYS6).
Platelet Glycoprotein antagonist
Etifibatide (integrilin) bụ akwụkwọ akụkọ polypeptide platelet glycoprotein IIb/IIIa antagonist nke na-egbochi nchịkọta platelet na thrombosis site na igbochi ụzọ ikpeazụ nke nchịkọta platelet. E jiri ya tụnyere monoclonal antibody abciximab, eptifibatide nwere njikọ siri ike, ntụzịaka na nke akọwapụtara na GPIIb/IIIa n'ihi ịdị adị nke otu nnọchi amino acid na-agbanwe agbanwe-lysine iji dochie arginine. Ya mere, ọ kwesịrị inwe mmetụta ọgwụgwọ dị mma na ntinye aka nke nnukwu ọrịa obi. Platelet glycoprotein IIb/IIIa antagonist antagonist emeputala nke ukwuu, ma ugbu a enwere ụdị nkwadebe atọ enwere ike iji na ụlọ ọgwụ na mba ụwa, abciximab, eptifibatide na tirofiban. ). Enweghi ahụmịhe dị nta n'iji platelet glycoprotein GPIIb/IIa ndị na-emegide ndị na-anabata ihe na China, yana ọgwụ ndị dịnụ nwekwara oke oke. Naanị otu ọgwụ, tirofiban hydrochloride, dị n'ahịa. Ya mere, e mepụtara platelet glycoprotein IIb ọhụrụ. /IIIa ndị na-emegide ndị na-anabata ya dị mkpa. Eptifibatide ụlọ bụ ngwaahịa nṅomi nke Chengdu Sino Biological Products Co., Ltd mepụtara.
Nhazi
Nhazi nke ọgwụ nchịkọta Antiplatelet
Enwere ike kewaa ọgwụ mgbochi antiplatelet ụzọ atọ: 1. Cyclooxygenase-1 (COX-1) inhibitors, dị ka aspirin. 2. Na-egbochi nchịkọta platelet na-akpata site na adenosine diphosphate (ADP), dị ka clopidogrel, prasugrel, cangrelor, ticagrelor, wdg. Akụkụ kemịkalụ arụpụtara ọhụrụ yana mpụta dị irè sitere na ọgwụ ọdịnala ndị China.
