Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

Fmoc-L-Lys[Eic(OtBu)-γ-Glu(OtBu)-AEEA-AEEA]-OH

Fmoc-L-Lys [Eic(OtBu)-γ-Glu(OtBu) -AEEA-AEEA] -OH bụ ngọngọ ụlọ amino acid arụrụ arụ ọrụ emebere maka nnyefe ọgwụ ezubere iche na bioconjugation. Ọ na-egosipụta moiety Eic (eicosanoid) maka mmekọrịta egbugbere ọnụ, γ-Glu maka ebumnuche, yana AEEA spacers maka mgbanwe.

 
Nyocha & Ngwa:

Ejiri ya na nhazi prodrug, mmepe ADC, na nanocarrier imewe

Na-akwalite nlebara anya akpụkpọ ahụ, solubility, na arụmọrụ njikọ

Kwesịrị ekwesị maka SPPS na nyocha njikọ ọgwụ peptide dị elu

Njirimara ngwaahịa (otu Gentolex):

Fmoc-echebe, ịdị ọcha dị elu (≥99%)

Nwere otu OtBu nwere ike ihichapụ maka njikọ a na-achịkwa

Fmoc-L-Lys [Eic(OtBu) -γ-Glu(OtBu) -AEEA-AEEA] -OH dị mma maka usoro nnyefe ziri ezi yana nhazi peptide arụ ọrụ.