Fmoc-Thr(tBu) -Phe-OH

Fmoc-Thr(tBu) -Phe-OH

Ngwa nyocha:
Fmoc-Thr (tBu) -Phe-OH bụ ngọngọ ụlọ dipeptide nke a na-ejikarị na njikọ peptide siri ike (SPPS). Otu Fmoc (9-fluorenylmethyloxycarbonyl) na-echebe N-terminus, ebe otu tBu (tert-butyl) na-echebe ụdọ akụkụ hydroxyl nke threonine. A na-amụ dipeptide a echedoro maka ọrụ ya n'ịkwado elongation peptide nke ọma, na-ebelata ịgba ọsọ, na ịdepụta ebumnuche usoro kpọmkwem na nhazi protein na ọmụmụ mmekọrịta.

Ọrụ:
Fmoc-Thr (tBu) -Phe-OH na-eje ozi dị ka ihe mmalite maka ịmepụta peptides nke gụnyere threonine na phenylalanine residues, nke dị mkpa maka ịmepụta njikọ hydrogen na mmekọrịta hydrophobic. Agbụ n'akụkụ threonine na-enye aka polarity na saịtị phosphorylation nwere ike, ebe phenylalanine na-agbakwunye àgwà aromatic na nkwụsi ike nhazi. Nchikota a bara uru n'ichepụta peptides maka nyocha nke ndu, ọmụmụ ihe na-ekekọta nnabata, na ngwa nchọpụta ọgwụ.