Leuprorelin acetate na-achịkwa ihe nzuzo nke homomis Gomadal
Nkọwa nke ngwaahịa
| Aha | Leuprorelin |
| Nọmba | 53714-56-0 |
| Molular | C59h84n16o12 |
| Molular ibu | 1209.4 |
| Nọmba einecs | 633-395-9 |
| Ntugharị kpọnwụrụ iche | D25 -31.7 Celsius (C = 1 na 1% acetic acid) |
| Keuju | 1.44 ± 0.1 g / cm3 (buru amụma) |
| Ọnọdụ nchekwa | -15 ° C |
| Odidi | Idiocha |
| Acidity coefy | (Pka) 9.82 ± 0,55 (buru amụma) |
| Mwepu mmiri | Soluble na mmiri na 1mg / ml |
Myiri
Lh-rlerololide; leuprolide (mmadu); leuprelin; -Nhet9) -Lenininghornormone-na-ewepụtaghachi;
Mmetụta ọgwụ
Leuprolide, Goselelin, Tribrelin, na Nafarelin bụ ọgwụ a na-ejikarị na ụlọ ọgwụ iji kwụsị ọrịa cancenopauces na ọrịa kansa. (zoro aka na ya dị ka gnrh-a ọgwụ), gnrh-a ọgwụ yiri nke GNRh ma soro ndị na-anabata ya gnrh. Nke ahụ bụ, Gnaadotropin zoro ezo na-ebelata, nke na-eduga na mbelata homonụ na mmekọahụ na-ezo.
Leuprolide bụ gomadotroping na-ahapụ ya analog (gnrh), peptide mejupụtara 9 amino acid. Ngwaahịa a nwere ike ikwegide ọrụ nke usoro piidary-gnadal, nguzogide nke enzrmes gnrh, na ọrụ nke ịkwalite ntọhapụ nke chronizite (lh) bụ ihe dị ka ugboro 20 nke gnrh. Ọ nwekwara mmetụta ndị na-egbochi ndị na-egbochi ya na Peturury-Gnad na-arụ ọrụ karịa GNRH. Na mbido ọgwụgwọ, Formocle akpali Hormone (FHTROGEN) nwere ike ịba ụba nwa oge, na-egbochi Androgen ma ọ bụ Estrogen ma ọ bụ ịdabere na homonụ mmekọahụ. Ọrịa nwoke na nwanyị (dịka ọrịa kansa, enumoosis, wdg) nwere mmetụta ọgwụgwọ.
Ugbu a, atetate nnu nke leuprolide bụ nke na-eji ụlọ na-arụsi ọrụ ike, n'ihi na arụmọrụ nke acerolide acetate na-akwụsi ike na ụlọ okpomọkụ. Ekwesịrị ịtụfu mmiri. Enwere ike iji ya maka ọgwụgwọ casterriosis na fibroids ọgwụ na uterine, ọrịa cander cander na onye na-agba ọbara ọbara, yana maka ọgwụgwọ homonụ nke na-enweghị ọgwụgwọ. A nwekwara ike iji ya dị ka ego tupu mmụba a, nke nwere ike ịmịghe ahụ, belata edema, ma belata nsogbu ịwa ahụ.
