Kedu ihe bụ Orforglipron?

Orforglipron bụ ụdị ọrịa shuga 2 nke ọhụrụ na ọgwụ ọgwụgwọ ọnwụ dị n'okpuru mmepe na a na-atụ anya ka ọ bụrụ ihe ọzọ na-eji ọnụ na ọgwụ injectable. Ọ bụ nke glucagon-dị ka peptide-1 (GLP-1) ezinụlọ agonist na-anabata ya ma yie nke Wegovy (Semaglutide) na Mounjaro (Tirzepatide) na-ejikarị. Ọ nwere ọrụ nke ịchịkwa shuga dị n'ọbara, na-egbochi agụụ na ịkwalite satiety, si otú ahụ na-enyere aka ịchịkwa ibu na ọkwa shuga ọbara.

N'adịghị ka ọtụtụ ọgwụ GLP-1, uru pụrụ iche nke Orforglipron bụ n'ụdị mbadamba ọnụ ya kwa ụbọchị karịa nchịkwa ịgba ọgwụ kwa izu ma ọ bụ kwa ụbọchị. Usoro nchịkwa a emeela ka ndị ọrịa nwee nrubeisi na ịdị mma nke iji ya, na-anọchite anya ọganihu dị mkpa maka ndị na-adịghị amasị injections ma ọ bụ nwere àgwà na-eguzogide ọgwụ maka injections.

N'ime ule ụlọ ọgwụ, Orforglipron gosipụtara mmetụta mbelata oke ibu. Data na-egosi na ndị sonyere na-ewere Orforglipron kwa ụbọchị maka izu 26 sochirinụ nwere mbelata ịdị arọ nke 8% ruo 12%, na-egosi na ọ bara uru na njikwa ibu. Nsonaazụ ndị a emeela Orforglipron olileanya ọhụrụ maka ọgwụgwọ ụdị ọrịa shuga 2 na oke ibu n'ọdịnihu, ma gosipụtakwa usoro dị mkpa na ngalaba ọgwụ GLP-1, nke na-agbanwe site na injectable gaa n'ụdị usoro onunu.