Orlistat 96829-58-2 na-emegharị nke abụba, na-ebute oke ibu
Nkọwa nke ngwaahịa
| Aha | Orlistat |
| Nọmba | 96829-56-2 |
| Molular | C29h53no5 |
| Molular ibu | 495.73 |
| Nọmba einecs | 639-75555-1 |
| Na-agbaze | <50 Celsius C |
| Keuju | 0.976 ± 0.06G / cm3 (buru amụma) |
| Ọnọdụ nchekwa | 2-8 ° C |
| Odidi | Nzu otite |
| Agba | Ucha |
| Acidity coefy | (Pka) 14.59 ± 0.23 (buru amụma) |
Myiri
(S) -2 -2 -2 -2-forylanino-4-methy-pentanocacid (s) -1, 3- hexyl]; () - Tetrahydratin; Orlistat; N-F Ormyl-L-leucine (1s) - [(2S, 3S) Methyl] Doodeclestersesters; Orlistatl (Sylistat); ORLISTETAT (Ferlistat)
Mmetụta ọgwụ
Olu
White crystalline ntụ ntụ, ọ fọrọ nke nta ka ọ bụrụ na mmiri, ọnya na-soluprom, sọpụ na methanol na ethanol, na-emegharị ya na-agbaze bụ 40 ℃ ~ 42 ~. Molekule ya bụ diasteromer nwere ebe chira anọ, na ebili mmiri nke 529nm, ngwọta Ethanol ya nwere ntụgharị anya na-adịghị mma.
Ọnọdụ nke ime
Orlistat bụ nnukwu ihe na-eme ihe na-arụ ọrụ na-arụ ọrụ na-arụ ọrụ na-arụ ọrụ, nke na-apụnara ihe dị ka enzymes abụọ dị elu site na saịtị seine na-arụ ọrụ na afọ na obere eriri afọ. Enzymes a na-ahụ anya na-enweghị ike imebi abụba n'ime nri na-eme ka ọ bụrụ abụba na Chemicalok glyceol nke nwere ike ịmịcha na ibelata ibu ma na-ebelata ibu. Na mgbakwunye, ọmụmụ ụfọdụ achọpụtala na ortlistat na-egbochi eriri afọ nke cholesterol site na igbochi NIEMN-Pick C1 (Nieman-pickc1-dịka1, NPC1L1).
Ngosiputa
A na-egosiputa ngwaahịa a na nri dicha nro maka ọgwụgwọ ogologo oge nke ndị buru ibu na nke buru ibu, gụnyere ndị nwere ihe ndị metụtara oke ihe metụtara oke ibu. Ngwaahịa a nwere njikwa ịdị arọ nke oge (njikwa ibu, mmezi na mgbochi nke resing). Iwere Orlistat nwere ike belata ihe ndị dị oke mkpa na ọrịa nke ọrịa ndị ọzọ metụtara, gụnyere ọrịa shuga, Hypensememia, ọbara mgbali elu, na akụkụ ndị ọzọ.
Mkpakọrịta ọgwụ
Nwere ike belata nnabata nke vitamin A, d na E. Enwere ike ịgbakwunye ya na ngwaahịa a n'otu oge. Ọ bụrụ na ị na-ewere nhazi nwere vitamin a, d na e (dịka ụfọdụ mutatimis), ị ga-ewere ngwaahịa a 2 awa mgbe iwere ngwaahịa a ma ọ bụ n'oge ụra. Ndị nwere ọrịa shuga nke Abụọ nke Abụọ nwere ike ịdị belata ọgwụ nke ọnụ hypoglycecces (dịka, sọlfọ). Nchịkwa na cyclosporine nwere ike ibute mbelata na plasma nwere ike itinye uche nke ndị ikpeazụ. Canomant ojiji nke amarorone nwere ike ibute mbelata nke nke ikpeazụ ma belata nrụrụ.
