REVERSE T3 maka njikọ protein, thermoregulation, mmepụta ike na nhazi
Nkọwa ngwaahịa
| Aha | Nghaghachi T3 |
| Nọmba CAS | 5817-39-0 |
| Usoro ihe omimi | C15H12I3NO4 |
| Ibu arọ molekụla | 650.97 |
| Ebe mgbaze | 234-238°C |
| Ebe esi nri | 534.6±50.0°C |
| Ịdị ọcha | 98% |
| Nchekwa | Debe ya n'ebe gbara ọchịchịrị, kpuchie ya na nkụ, chekwaa ya na friza, n'okpuru -20 Celsius |
| Ụdị | Ntụ ntụ |
| Agba | Pale Beige ruo Brown |
| Nkwakọ ngwaahịa | Akpa PE+Aluminom akpa |
Ụdị okwu
ReverseT3 (3,3',5'-Triiodo-L-Thyronine);L-Tyrosine, O- (4-hydroxy-3,5-diiodophenyl) -3-iodo-; (2S) -2-aMino-3-[4- (4-hydroxy-3,5-diiodophe noxy)-3-iodophenyl]propanoicacid; REVERSET3;T3;LIOTHYRONIN;L-3,3',5'-TRIIODOTHYRONINE;3,3′,5'-Triiodo-L-thyronine(ReverseT3) ngwọta
Mmetụta ọgwụ
Nkọwa
Ọkpụkpụ thyroid bụ gland endocrine kachasị na ahụ mmadụ, yana ihe ndị bụ isi na-arụ ọrụ zoro ezo bụ tetraiodothyronine (T4) na triiodothyronine (T3), nke dị oke mkpa maka njikọ protein, nhazi okpomọkụ, mmepụta ume na ọrụ nhazi. Ọtụtụ n'ime T3 dị na serum na-agbanwe site na deiodination anụ ahụ dị n'akụkụ, na obere akụkụ nke T3 bụ nke thyroid zoro ezo ozugbo wee hapụ ya n'ime ọbara. Ọtụtụ n'ime T3 na serum na-ejikọta na protein na-ejikọta, ihe dị ka 90% nke na-ejikọta ya na thyroxine-binding globulin (TBG), nke fọdụrụ na-ejikọta na albumin, na obere ego na-ejikọta ya na thyroxine-binding prealbumin (TBPA). Ọdịnaya nke T3 na serum bụ 1 / 80-1 / 50 nke T4, mana ọrụ ndu nke T3 bụ 5-10 ugboro T4. T3 na-arụ ọrụ dị mkpa n'ikpe ikpe ọnọdụ physiological nke ahụ mmadụ, n'ihi ya, ọ dị oke mkpa ịchọpụta ọdịnaya T3 na serum.
Mkpa ụlọ ọgwụ
Mkpebi nke triiodothyronine bụ otu n'ime ihe na-egosi mmetụta dị nro maka nchoputa nke hyperthyroidism. Mgbe hyperthyroidism na-abawanye, ọ bụkwa ihe mmalite maka nlọghachi nke hyperthyroidism. Na mgbakwunye, ọ ga-abawanye n'oge ime ime na nnukwu ịba ọcha n'anya. Hypothyroidism, mfe goiter, nnukwu na-adịghị ala ala nephritis, ala ala ịba ọcha n'anya, imeju cirrhosis ebelata. Serum T3 ntinye uche na-egosipụta ọrụ nke thyroid gland na anụ ahụ gbara ya gburugburu karịa ọnọdụ nzuzo nke thyroid gland. Enwere ike iji mkpebi T3 mee ihe maka nyocha nke T3-hyperthyroidism, nchọpụta hyperthyroidism n'oge na nchọpụta nke pseudothyrotoxicosis. Ngụkọta ọkwa ọbara T3 na-adaberekarị na mgbanwe nke ọkwa T4. Ọ bụ ihe na-egosi mmetụta dị nro maka nchoputa nke ọrụ thyroid, karịsịa maka nchọpụta mbụ. Ọ bụ ihe nchọpụta akọwapụtara maka T3 hyperthyroidism, mana ọ nwere ntakịrị uru maka nyocha nke ọrụ thyroid. Maka ndị ọrịa na-eji ọgwụ thyroid agwọ ọrịa, a ga-ejikọta ya na mkpokọta thyroxine (TT4) na, ọ bụrụ na ọ dị mkpa, thyrotropin (TSH) n'otu oge iji nyere aka ikpebi ọnọdụ ọrụ thyroid.
