A na-eji RU-58841 mee ihe dị ka mgbochi ntutu isi na isi nkwọcha nke nwoke
Nkọwa ngwaahịa
| Aha | RU-58841 |
| Nọmba CAS | 154992-24-2 |
| Usoro ihe omimi | C17H18F3N3O3 |
| Ibu arọ molekụla | 369.34 |
| Nọmba EINECS | 1592732-453-0 |
| Ebe esi nri | 493.6± 55.0 °C(buru amụma) |
| Njupụta | 1.39 |
| Ọnọdụ nchekwa | E mechiri ya na nkụ, chekwaa na friza, n'okpuru -20 Celsius |
| Ụdị | Ntụ ntụ |
| Agba | Ọcha |
| Nkwakọ ngwaahịa | Akpa PE+Aluminom akpa |
Ụdị okwu
RU58841; 4- (4,4-Dimethyl-2,5-dioxo-3- (4-hydroxybutyl) 1-imidazolidinyl) -2- (trifluoromethyl) benzonitrile; 4- [3- (4-Hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-ben-2- (trifluoromethyl). onitrile; 4-[3- (4-Hydroxybutyl) -4,4-diMethyl-2,5-dioxoiMidazolidin-1-yl]-2- (trifluoroMethyl) ben zonitrile; RU-58841E: candyli (na) speedgainpharma (dot) com; CS-637; RU588841; RU58841; RU58841; RU-58841
Mmetụta ọgwụ
Nkọwa
RU 58841 (PSK-3841) bụ antagonist androgen receptor antagonist na-akwalite uto ntutu.RU58841 bụ ọgwụ nyocha emepụtara maka ọgwụgwọ megide alopecia androgenic, nke a makwaara dị ka isi nkwọcha nwoke (MPD).
Dị ka ihe mgbochi-androgen a na-ahụ anya, ụkpụrụ omume ya abụghị otu nke finasteride. Finasteride na-arụ ọrụ ozugbo na 5a reductase, na-egbochi ntụgharị nke testosterone n'ime DHT, ma belata ọdịnaya nke DHT n'ime ahụ. RU58841 na-egbochi kọntaktị dị n'etiti dihydrotestosterone na ndị na-anabata ntutu isi, ọ naghị ebelata ọdịnaya DHT ozugbo, ma ọ na-ebelata njikọ nke DHT na ndị na-anabata ntutu isi, iji nweta nzube nke ịgwọ androgenetic alopecia.
4-[3- (4-Hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2- (trifluoromethyl) benzonitrile nwere ike iji dị ka ọgwụ Chemical synthesis intermediates.Ọ bụrụ na 4-[3- (4-hydroxybutyl) -4,4-dimethyl-2,5-dioxo-1-imidazolidinyl] -2- (trifluoromethyl) benzonitrile na-eku ume, Bugharịa onye ọrịa na ikuku ọhụrụ;N'ihe gbasara mmetụ akpụkpọ ahụ, wepụ uwe emerụ emerụ, sachaa akpụkpọ ahụ nke ọma na ncha na mmiri, ma chọọ nlekọta ahụike ma ọ bụrụ na ahụ erughị ala;
Mmetụta
A na-etinye RU58841 n'akpụkpọ isi, na-etinye ya na ntutu isi, na usoro, ọ nwere ike ịbanye n'ọbara ma na-emetụta akụkụ ahụ ndị ọzọ. Mana ọnweghị mmetụta dị n'usoro ahụ achọpụtala na nyocha nke ngwa n'elu n'ime enwe. Otú ọ dị, ụfọdụ ndị nwara RU58841 na-azọrọ na ha enwetala ụfọdụ mmetụta ndị nwere ike ime site na iji RU, gụnyere mgbakasị akpụkpọ ahụ, mbelata libido, nkwụsị nke erectile, ọgbụgbọ, anya uhie, dizziness, na isi ọwụwa.
