Tirzepatide Lyophilized High Purity 99% Peptide Powder 60mg kwa vial maka ọrịa shuga na ọnwụ dị arọ.

Tirzepatide Lyophilized ntụ ntụ (60 mg)

Tirzepatide (LY3298176) bụ agonist nke mbụ na-eme ihe abụọ na-elekwasị anya ma GIP (glucose-based insulinotropic polypeptide) na GLP-1 (glucagon-dị ka peptide-1). Ọ natara nkwado US FDA na Mee 2022 maka ọgwụgwọ ụdị ọrịa shuga mellitus 2 (T2DM) dị ka ihe mgbakwunye nri na mmega ahụ.
A na-enye ngwaahịa a ka ọ bụrụ 60mg lyophilized (frize-dried) ntụ ntụ na-adịghị mma na vials, nke a ga-eji mmiri bacteriostatic megharịa tupu nchịkwa. E jiri ya tụnyere otu GLP-1 agonists ndị na-anabata ya dị ka semaglutide ma ọ bụ dulaglutide, tirzepatide na-egosipụta arụmọrụ dị elu n'ịkwalite usoro glucose ọbara, na-eme ka mmetụta insulin dịkwuo elu, na ịkwado oke ibu. A na-ekwu na uru ndị a sitere na usoro ihe omume synergistic dual-receptor.

Uru isi
Njikwa glycemic

• Na-akpali mmepụta insulin n'ụzọ dabere na glucose
• Na-ebelata ihe nzuzo nke glucagon, na-ebelata ọkwa glucose ọbara nke ọma
• Na-egosipụta mmetụta metabolic jikọtara ọnụ nke ma GIP na GLP-1

Njikwa ibu

• Na-akwalite satiety ma na-ebelata oriri caloric
• Egosiputara oke ibu na nkwụsi ike na ọmụmụ ụlọ ọgwụ

Ahụike obi

• Ihe omuma nke mbu gosiri na enwere ike ibelata ihe egwu obi na ndi oria nwere T2DM

Ojiji na usoro onunu ogwu

• Tirzepatide lyophilized ntụ ntụ (60 mg) kwesịrị iji mmiri bacteriostatic mee ka ọ dịghachi tupu ejiri ya. Nlekọta bụ site n'ịgba ọgwụ subcutaneous, ọ na-abụkarị otu ugboro kwa izu n'otu ụbọchị ahụ kwa izu.

Ụdị ọrịa shuga 2

• Usoro mmalite: 2.5 mg otu ugboro kwa izu
• Titration: Na-abawanye kwa izu anọ dịka anabatara
• (→ 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg → 20 mg → 30 mg → 45 mg → to 60 mg)
• Usoro a na-ahụkarị: 10-30 mg kwa izu
• Oke kachasị: 60 mg kwa izu

Ijikwa oke ibu / ibu

• Usoro mmalite: 2.5 mg otu ugboro kwa izu
• Titration: Mwelite dose nke nta nke nta ka anabatara ya
• (2.5 → 5 → 7.5 → 10 → 12.5 → 15 → 20 → 30 → 45 → 60 mg )
• Usoro a na-ahụkarị: 30-60 mg kwa izu
• Oke kachasị: 60 mg kwa izu

Ntụle usoro onunu ogwu akwadoro

Mara:Gbaa mbọ hụ na a nabatara ọgwụ ọ bụla gara aga nke ọma tupu abawanye.

Mmeghachi omume ọjọọ enwere ike

• Gastrointestinal: ọgbụgbọ, ọgbụgbọ, afọ ọsịsa, na ahụ erughị ala afọ (na-emekarị n'oge mmalite)
• Hypoglycemia: Ihe ize ndụ dị obere, mana ọ na-abawanye mgbe ejiri ya na ọgwụ antidiabetic ndị ọzọ
• Mmeghachi omume saịtị ịgba ọgwụ: ọbara ọbara, itching, ọzịza, ma ọ bụ obere mgbu na saịtị ahụ
• Pancreatitis: dị ụkọ ma ọ ga-ekwe omume; nyochaa maka mgbu afọ na-adịgide adịgide
• Mmetụta gbasara akụrụ: Enwere ike ịchọ nlekota ọrụ akụrụ na ụfọdụ ndị mmadụ

Pharmacokinetics

• Ọkara-ndụ: Ihe dị ka otu izu
• Ugboro dose: Na-akwado nchịkwa dị mma otu ugboro kwa izu

Nchịkọta
Tirzepatide 60 mg lyophilized ntụ ntụ na-anọchite anya ọganihu ọgwụgwọ ọgbọ na-esote, na-ejikọta njikwa glycemic dị ike na ịdị irè ọnwụ dị ịrịba ama na nchebe obi.
Site na nhazi oge nke ntanye nke nta nke nta (2.5 mg → ruo 60 mg), ọ na-enye ohere nkwalite na mgbanwe maka ọgwụgwọ onwe onye. Nlekọta ya otu ugboro kwa izu na-eme ka nrube isi, na-eme ka ọ bụrụ nhọrọ ọhụrụ na nke dị irè maka njikwa ụdị ọrịa shuga 2 na oke ibu na ụlọ ọgwụ dị elu na ntọala nyocha.