Ganirelix Acetate Peptide API

Nkọwa dị mkpirikpi:

Aha: Ganirelix Acetate

Nọmba CAS: 123246-29-7

Usoro ihe omimi: C80H113ClN18O13

Ibu ibu: 1570.34

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Nkọwa ngwaahịa

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Nkọwa ngwaahịa

Aha	Ganirelix acetate
Nọmba CAS	123246-29-7
Usoro ihe omimi	C80H113ClN18O13
Ibu molekụla	1570.34

Ụdị okwu

Ac-DNal-DCpa-DPal-Ser-Tyr-DHar (Et2) -Leu-Har (Et2) -Pro-DAla -NH2; Ganirelixum;ganirelix Acetate;GANIRELIX;Ganirelix Acetate USP/EP/

Nkọwa

Ganirelix bụ ogige decapeptide sịntetik, na nnu acetate ya, Ganirelix acetate bụ onye na-anabata homonụ na-ahapụ gonadotropin (GnRH).Usoro amino acid bụ: Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-Tyr-D-HomoArg(9,10-Et2)-Leu-L-HomoArg(9,10-Et2)-Pro- D- Ala-NH2.tumadi na ụlọ ọgwụ, a na-eji ya na ụmụ nwanyị na-enye aka na teknụzụ ịmụ nwa na-achịkwa mmemme mkpali ovarian iji gbochie ọnụ ọgụgụ hormone luteinizing na-akabeghị aka yana ịgwọ nsogbu ọmụmụ n'ihi nke a.Ọgwụ ahụ nwere njirimara nke mmeghachi omume na-adịghị mma, ọnụ ọgụgụ dị elu nke ime ime na oge ọgwụgwọ dị mkpirikpi, ma nwee uru doro anya ma e jiri ya tụnyere ọgwụ ndị yiri ya na omume ụlọ ọgwụ.

Omume ọgwụ

Mwepụta pulsatile nke gonadotropin na-ahapụ homonụ (GnRH) na-akpali njikọ na nzuzo nke LH na FSH.Ugboro nke mmụgharị LH n'etiti etiti na ngwụcha usoro follicular bụ ihe dịka 1 kwa elekere.Mmụba ndị a na-egosipụta na ịrị elu nwa oge na serum LH.N'ime etiti oge ịhụ nsọ, nnukwu mwepụta nke GnRH na-ebute mmụba nke LH.Mwapụta LH etiti oge ịhụ nsọ nwere ike ịkpalite ọtụtụ nzaghachi anụ ahụ, gụnyere: ovulation, oocyte meiotic resumption, na nhazi corpus luteum.Nhazi nke corpus luteum na-eme ka ọkwa nke progesterone serum na-ebili, ebe ọkwa estradiol dara.Ganirelix acetate bụ onye na-emegide GnRH nke na-asọ mpi na-egbochi ndị na-anabata GnRH na pituitary gonadotrophs na ụzọ ntụgharị na-esote.Ọ na-emepụta ihe mgbochi nke gonadotropin ngwa ngwa, nke na-agbanwe agbanwe.Mmetụta mgbochi nke ganirelix acetate na nzuzo pituitary LH siri ike karịa nke ahụ na FSH.Ganirelix acetate emeghị ka ntọhapụ mbụ nke gonadotropins endogenous, na-adabere na antagonism.Ngwọta zuru oke nke ọkwa pituitary LH na FSH mere n'ime awa 48 ka a kwụsịrị ganirelix acetate.

Nke gara aga: Cetrorelix Acetate iji gbochie ịmụ nwa 120287-85-6

Osote: Linaclotide maka Ọrịa Gastrointestinal 851199-59-2

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