Ibutamonen Meslete na-abawanye uru dị oke ọnụ, ọkwa 1 na Ghọ ọkwa
Nkọwa nke ngwaahịa
| Aha | Ibutamonen Meslete |
| Nọmba | 159752-10-0 |
| Molular | C28h40n4O8s2 |
| Molular ibu | 624.77 |
| Nọmba einecs | 1308068-626-2 |
| Na-agbaze | 164-170 Celsius C |
| Soluuru | H2O: soluble5mg / ml, doo anya |
| Ọnọdụ nchekwa | 2-8 ° C |
| Odidi | Nzu otite |
| Agba | Ọcha na beige |
| Mbukota | Akpa Pear + Aluminom akpa |
Myiri
Mk-677; 2-amino-n - [(1r) -2- Diihydronyl) -1'-piperiding] -1'-yl] -1'-thyl] ethyl] ethyl] rie; mk677 (ibutamorenmesyyyyyyyyyyyyyyyyyyyylate); mk0677; mk0677; mk0677; mk677; mk677; c S-1402; MK6777MUTAMEN; MK677MUTEN, WHNOHE_LUCY (na) 163.com; mk677, MK677, MK677
Mmetụta ọgwụ
Nkowa
Misleten bụ ọgwụ na-arụ ọrụ dị ka onye nwere ike, ma ọ bụ ike, uto na-akpali ihe nzuzo hormone, na-eme ka ihe ógbè ahụ mee ihe iji kpalie homonụ endogen.
Oru oruru
Egosiputala Mesleten Meslete ka ịbawanye ntọhapụ na mmepụta nke na-arụsi ọrụ ike nke ụfọdụ homones 1 (IGF-1), mana anaghị emetụta ọkwa cortisol. Ọgwụ nwere ike ịwepụta ugbu a n'okpuru mmepe nke homonụ ndị a, dị ka na ụmụaka ma ọ bụ ndị agadi egosiwo mmụba nke mmụọ, na-eme ka ọ gwọọ ndị okenye na-akụzi. Ọ na-agbanweta metabolism nke abụba ahụ, yabụ ọ nwere ike ịnwe ngwa na ọgwụgwọ nke oke ibu.
Na ọmụmụ ihe vivo
Ibutamonen Meslete (5 mg / day) na-ebute ọnụ ọgụgụ dị ukwuu na-abawanye ibu dị elu ma na-abawanye na nkịta. Ibutamoren na-esite na ndapụta na-enweghị mmụba dị ukwuu na CSF IGF-1 ma ọ bụ n 'ọkwa na ụbọchị 7 ma ọ bụ 15 nke ọmụmụ ahụ. Ime ka ụmụ oke na-eme ihe ike na-emegharị nke neurons ndị a site na Ibutamonen Meslete (50 μg, IP). N'ime ụmụ oke, ma hrtraotide anaghị egbochi ibutamonen Meslete ịgbalite nke ịkọ neurons. Nchịkọta na-adịghị ala ala nke MK-0677 na-ejikọ ọnụ na mmụba dị ukwuu na Gh na Igf-m ọkwa dị na ọkwa ndị a na-enwe maka oge ọgwụgwọ. Pụrụ Profaịlụ na-esote Mk-0677 nchịkwa mejupụtara na-abawanye na-abawanye elu. Mk-0677 na-abawanye ụba na-abawanye ụba mgbe nchịkọta ọnụ. Mk-0677 bụ onye na-eme ihe nzuzo na-eme ihe nzuzo, buru ibu, na-abawanye na ọkwa nke hle na-adịgide ma ọ bụ nke a
