Terlipressin acetate maka esphageal ọgbụgba
Nkọwa nke ngwaahịa
| Aha | N- (n-glycyllycyl) glycyl) -8-l-lsininevasoptsin |
| Nọmba | 14636-12-5 |
| Molular | C52H74N16O15s2 |
| Molular ibu | 1227.37 |
| Nọmba einecs | 238-680-8 |
| Isi mmiri | 1824.0 ± 65.0 Celsius C (buru amụma) |
| Keuju | 1.46 ± 0.1 g / cm3 (buru amụma) |
| Ọnọdụ nchekwa | Debe ebe gbara ọchịchịrị, ebe a na-echegharị, chekwaa na friza, n'okpuru -15 Celsius. |
| Acidity coefy | (pka) 9.90 ± 0,15 (buru amụma) |
Myiri
[N-α-triglycyl-8-Lysine]-80: pn: WO201003320332033207Sekin; 1-triglycyl-8-Lshinevasopressin; Nα-glycyl-glycyl-glycyl- [8-Lysine] -n toopvassin; Nα-glycyl-glycyl-glycyl-lisine-vesine-vasoopressin; Nα-glycylgylgylcyl-vasoopressin; Nα gly-gly-gly-gly-ly-Vasopressin; Terlipressin, Terlipressone, Terlipsertina, Terlipressin.
Nkowa
Terlipressin, onye aha kemịkalụ bụ ihe na-ewu ewu na Vsopressin Vsopressin, bụ nkwadebe sythetik ogologo oge. Ọ bụ ụdị prodsug, nke na-abụghị naanị ya. Ọ na-eme ya site na aminopeptinase na vivo iji nwayọ "wepụta" ndị ọrụ Lysine na-arụ ọrụ mgbe iwepu ihe ndị a na-akụ glycy na n-opeké. Ya mere, Terlipressin na-arụ ọrụ dị ka ebe nchekwa na-ewepụta Lysine Vsopresson na ọnụego ọnụego.
Mmetụta ọgwụ terlipressin bụ iji nkwekọrịta vaskụba vaskụọ dị mma ma belata ọbara na-agba agba agba agba agba agba agba agba agba agba agba agba agba agba agba na-agbadata. N'aka nke ọzọ, ọ nwekwara ike belata planma ahụ nsonaazụ ntụgharị, si otú ahụ na-abawanye ụba ọbara, na-eme ka ọ na-arụ ọrụ mmanye na ọrịa na-arụ ọrụ na hepaatonal. Terlipressin bụ ugbu a ọgwụ nwere ike ime ka ọnụego ndị ọrịa na-enwe ike ịdị nlanarị na esphageal Vanarrmage. A na-ejikarị ya na ọgwụgwọ ọgwụ nke ọbara ọbara. Na mgbakwunye, a na-ejikwa terlipressin nke ọma na imeju na akụrụ. Na mkpokọta, o nwere ike ịbụ na ọ ga-ekere òkè bara uru na njikọta ọnụ na-ada ụda nke ujo na mgbakwunye candiopulmonary. E jiri ya tụnyere Vsopressin, ọ nwere mmetụta na-adịgide adịgide, anaghị akpata nsogbu dị ize ndụ, gụnyere mgbatị ahụ dị mfe iji (nke ga-adabara nke ọma. Nnapụta na ọgwụgwọ nke ndị ọrịa na-arịa ọrịa siri ike.
