Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU

Ste-γ-Glu-AEEA-AEEA-OSU bụ molekul njikọ lipidated synthetic emebere maka nnyefe ọgwụ ezubere iche yana mgbochi-ọgwụ conjugates (ADCs). Ọ nwere ọdụ stearoyl (Ste) hydrophobic, γ-glutamyl ezubere iche motif, AEEA spacers maka mgbanwe, yana otu OSu (NHS ester) maka njikọta nke ọma.

 
Nyocha & Ngwa:

Ejiri ya na nhazi prodrug ezubere iche na ime nanocarrier

Na-akwalite mmekọrịta nke akpụkpọ ahụ cell na iwere ọgwụ

Na-eme ka ntinye ụgwọ ụgwọ saịtị akọwapụtara na peptides, ọgwụ mgbochi ọrịa, ma ọ bụ ndị na-ebu

Njirimara ngwaahịa (otu Gentolex):

Ịdị ọcha dị elu, ester dị njikere ijikọ ọnụ

Kwesịrị ekwesị maka nyocha bioconjugation na nnyefe ezubere iche

Ste-γ-Glu-AEEA-AEEA-OSU dị mma maka mmepe usoro nnyefe ọgwụ nkenke.